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Visualization in Connectomics

Hanspeter Pfister, Verena Kaynig, Charl P. Botha, Stefan Bruckner, V. J. Dercksen, Hans-Christian Hege, and Jos B. T. M. Roerdink

FU maps for multichannel EEG coherence visualization. Brain responses were collected from three subjects using an EEG cap with 119 scalp electrodes. During a so-called P300 experiment, each participant was instructed to count target tones of 2000Hz (probability 0.15), alternated with standard tones of 1000Hz (probability 0.85) which were to be ignored. After the experiment, the participant had to report the number of perceived target tones. Shown are FU maps for target stimuli data, with FUs larger than 5 cells, for the 1-3Hz EEG frequency band (top row) and for 13-20Hz (bottom row), for three datasets.

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Connectomics is a field of neuroscience that analyzes neuronal connections. A connectome is a complete map of a neuronal system, comprising all neuronal connections between its structures. The term "connectome" is close to the word "genome" and implies completeness of all neuronal connections, in the same way as a genome is a complete listing of all nucleotide sequences. The goal of connectomics is to create a complete representation of the brain's wiring. Such a representation is believed to increase our understanding of how functional brain states emerge from their underlying anatomical structure. Furthermore, it can provide important information for the cure of neuronal dysfunctions like schizophrenia or autism. In this paper, we review the current state-of-the-art of visualization and image processing techniques in the field of connectomics and describe some remaining challenges.

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Citation

Hanspeter Pfister, Verena Kaynig, Charl P. Botha, Stefan Bruckner, V. J. Dercksen, Hans-Christian Hege, and Jos B. T. M. Roerdink, Visualization in Connectomics, CoRR, abs/1206.1428, 2012.

BibTex 

@article{bib:pfister:2012,
    author       = { Pfister, Hanspeter and Kaynig, Verena and Botha, Charl P. and Bruckner, Stefan and Dercksen, V. J. and Hege, Hans-Christian and Roerdink, Jos B. T. M. },    
    title        = { Visualization in Connectomics },
    journal      = { CoRR },
    volume       = { abs/1206.1428 },
    year         = { 2012 },
    dblp         = { journals/corr/abs-1206-1428 },
    url          = { https://publications.graphics.tudelft.nl/papers/316 },
}